Rhabdomyolysis is a muscle damage that manifests by releasing potentially toxic substances from injured cells to blood plasma. Diagnosis confirms i.e. elevated concentration of myoglobin, creatine kinase (CK), lactate dehydrogenase (LHD), aspartate transaminase (AspAT) and alanine transaminase (ALAT).
This study presents the case of a 30-year-old man in which an exertional rhabdomyolysis incident complicated with severe renal failure that demanded hemodialysis occurred. After the incident there also appeared episodes of pain and muscle swellings of lower limbs combined with elevated level of CK.
Risk factors recognized in this young patient were: spinning, taking hypolipidemic agents due to combined dyslipideamia, undergone viral infection and conditions favouring lower limbs ischaemia. Recurring rhabdomyolysis incidents in this patient and medical history of his family convince us that inclusion of genetic examination into further diagnostics is necessary.More »
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Jason Roberts, Eduardo Savine Mayr, Dominik Rymer, Bartosz Zielski